Anticonvulsant activities of friedelan-3-one and n-dotriacontane both isolated from Harungana madagascariensis Lam (Hypericaceae) seeds extracts
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چکیده
منابع مشابه
Anti-protozoan activities of Harungana madagascariensis stem bark extract on trichomonads and malaria.
AIM OF THE STUDY The ethanolic stem bark extract of Harungana madagascariensis (Hypericaceae), (Choisy) Poir were evaluated for their activities on Trichomonas gallinae (Rivolta) Stabler isolated from the pigeon (Columba livia). It was also tested for their anti-malarial activity on N67 Plasmodium yoelii nigeriensis (in vivo) in mice and on Plasmodium falciparum isolates in vitro. MATERIALS A...
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Some 6-aryl-4,5-dihydropyridazin-3(2H)-one compounds (2a-f) were synthesized and evaluated for their in-vivo anticonvulsant activities against maximal electro shock (MES) and isoniazid (INH) induced seizure methods at 50mg/kg dose level. Neurotoxicity of all compounds (2a-f) was also tested at 50, 100 and 200mg/kg dose level. The in-vitro antitubercular activity was evaluated against Mycobacter...
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A series of 4-N-substituted arylsemicarbazones with increased lipophilicity were synthesized and evaluated for anticonvulsant activity. The compounds provided significant protection against maximal electroshock induced seizures (MES) and seizures indicated by sc pentetrazole administration (sc PTZ) at 300 mg/kg after 0.5 h. The compounds 8 and 4 were active in MES and sc PTZ indicated seizure. ...
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BACKGROUND The extract from Moringa oleifera seeds is used worldwide, especially in rural areas of developing countries, to treat drinking water. M. oleifera seeds contain the lectins cmol and WSMoL, which are carbohydrate-binding proteins that are able to reduce water turbidity because of their coagulant activity. Studies investigating the ability of natural products to damage normal cells are...
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Ferulago species have been utilized since ancient times as digestive, sedative, aphrodisiac, along with in salads or as a spice due to their special odors. The study reports isolation and characterization of bioactive compounds of Ferulago pachyloba (F. pachyloba), Ferulago trachycarpa (F. trachycarpa), Ferulago bracteata (F. bracteata), and Feru...
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ژورنال
عنوان ژورنال: Journal of Medicinal Plants Research
سال: 2020
ISSN: 1996-0875
DOI: 10.5897/jmpr2020.7002